arrested B cell differentiation_Cd79b<tm1Mnz>/Cd79b<tm1Mnz>,Tg(IghelMD4)4Ccg/0,Tg(Rag2-Igb)1Mnz/0

http://metadb.riken.jp/0001802I129S1SvC57BL6Cd79btm1MnzCd79btm1MnzTgIghelMD44Ccg0TgRag2Igb1Mnz0TgIghelMD44CcgTgRag2Igb1MnzCd79btm1Mnz

arrested B cell differentiation_Cd79b<tm1Mnz>/Cd79b<tm1Mnz>,Tg(IghelMD4)4Ccg/0,Tg(Rag2-Igb)1Mnz/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Michel C Nussenzweig
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388293
• transgene insertion 4, Christopher C Goodnow
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053738
• CD79B antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:96431

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd79b<tm1Mnz>/Cd79b<tm1Mnz>,Tg(IghelMD4)4Ccg/0,Tg(Rag2-Igb)1Mnz/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(IghelMD4)4Ccg|Tg(Rag2-Igb)1Mnz|Cd79b<tm1Mnz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• arrested B cell differentiation
  http://purl.obolibrary.org/obo/MP_0001802

文献

http://purl.org/net/cito/citesAsAuthority

• Eric. Meffre, et.al., Deletion of immunoglobulin beta in developing B cells leads to cell death., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99
  http://rdf.ncbi.nlm.nih.gov/pubmed/12165571