arrested B cell differentiation_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>,Igk-J<tm2.1(4E10)Lave>/Igk-J<tm2.1(4E10)Lave>

http://metadb.riken.jp/0001802IC57BL6IghJtm214E10LaveIghJtm214E10LaveIgkJtm214E10LaveIgkJtm214E10LaveIgkJtm214E10LaveIghJtm214E10Lave

arrested B cell differentiation_Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>,Igk-J<tm2.1(4E10)Lave>/Igk-J<tm2.1(4E10)Lave>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin kappa chain, joining region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96497
• immunoglobulin heavy chain, joining region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96461

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh-J<tm2.1(4E10)Lave>/Igh-J<tm2.1(4E10)Lave>,Igk-J<tm2.1(4E10)Lave>/Igk-J<tm2.1(4E10)Lave>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igk-J<tm2.1(4E10)Lave>|Igh-J<tm2.1(4E10)Lave>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• arrested B cell differentiation
  http://purl.obolibrary.org/obo/MP_0001802

文献

http://purl.org/net/cito/citesAsAuthority

• Yao. Chen, et.al., Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10., Journal of immunology (Baltimore, Md. : 1950), 2013, 191
  http://rdf.ncbi.nlm.nih.gov/pubmed/23825311