decreased IgG level_Cr2<tm1Crr>/Cr2<tm1Crr>

http://metadb.riken.jp/0001805I129S7SvEvBrdC57BL6Cr2tm1CrrCr2tm1CrrCr2tm1Crr

decreased IgG level_Cr2<tm1Crr>/Cr2<tm1Crr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• complement receptor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:88489

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cr2<tm1Crr>/Cr2<tm1Crr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cr2<tm1Crr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased IgG level
  http://purl.obolibrary.org/obo/MP_0001805

文献

http://purl.org/net/cito/citesAsAuthority

• Z. Chen, et.al., Humoral immune responses in Cr2-/- mice: enhanced affinity maturation but impaired antibody persistence., Journal of immunology (Baltimore, Md. : 1950), 2000, 164
  http://rdf.ncbi.nlm.nih.gov/pubmed/10779753
• J M. Ahearn, et.al., Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen., Immunity, 1996, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/8624815