decreased IgM level_Cd79a<tm4Cgn>/Cd79a<tm4.1Cgn>,Tg(Cr2-cre)3Cgn/0

http://metadb.riken.jp/0001806I129P2OlaHsdC57BL6Cd79atm4CgnCd79atm41CgnTgCr2cre3Cgn0TgCr2cre3CgnCd79atm4CgnCd79atm41Cgn

decreased IgM level_Cd79a<tm4Cgn>/Cd79a<tm4.1Cgn>,Tg(Cr2-cre)3Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 3, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:3708319
• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd79a<tm4Cgn>/Cd79a<tm4.1Cgn>,Tg(Cr2-cre)3Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cr2-cre)3Cgn|Cd79a<tm4Cgn>|Cd79a<tm4.1Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased IgM level
  http://purl.obolibrary.org/obo/MP_0001806

文献

http://purl.org/net/cito/citesAsAuthority

• Manfred. Kraus, et.al., Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer., Cell, 2004, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/15186779