decreased IgA level_Igha<tm1Grh>/Igha<tm1Grh>

http://metadb.riken.jp/0001807I129S7SvEvBrdC57BL6Ighatm1GrhIghatm1GrhIghatm1Grh

decreased IgA level_Igha<tm1Grh>/Igha<tm1Grh>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy constant alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:96444

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igha<tm1Grh>/Igha<tm1Grh>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igha<tm1Grh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased IgA level
  http://purl.obolibrary.org/obo/MP_0001807

文献

http://purl.org/net/cito/citesAsAuthority

• G R. Harriman, et.al., Targeted deletion of the IgA constant region in mice leads to IgA deficiency with alterations in expression of other Ig isotypes., Journal of immunology (Baltimore, Md. : 1950), 1999, 162
  http://rdf.ncbi.nlm.nih.gov/pubmed/10072491
• B P. Arulanandam, et.al., IgA immunodeficiency leads to inadequate Th cell priming and increased susceptibility to influenza virus infection., Journal of immunology (Baltimore, Md. : 1950), 2001, 166
  http://rdf.ncbi.nlm.nih.gov/pubmed/11123296