decreased activated T cell number_Fadd<tm1Wnt>/Fadd<tm1Wnt>,Tg(Fadd/EGFP)#Jizh/?,Tg(Cd4-cre)1Cwi/?

http://metadb.riken.jp/0001830I129S4SvJaeC57BL6DBA2Faddtm1WntFaddtm1WntTgFaddEGFPJizhTgCd4cre1CwiTgCd4cre1CwiTgFaddEGFPJizhFaddtm1Wnt

decreased activated T cell number_Fadd<tm1Wnt>/Fadd<tm1Wnt>,Tg(Fadd/EGFP)#Jizh/?,Tg(Cd4-cre)1Cwi/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• Fas (TNFRSF6)-associated via death domain
  http://metadb.riken.jp/db/mgi_rdf/MGI:109324
• transgene insertion, Jianke Zhang
  http://metadb.riken.jp/db/mgi_rdf/MGI:4943141

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fadd<tm1Wnt>/Fadd<tm1Wnt>,Tg(Fadd/EGFP)#Jizh/?,Tg(Cd4-cre)1Cwi/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Tg(Fadd/EGFP)#Jizh|Fadd<tm1Wnt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased activated T cell number
  http://purl.obolibrary.org/obo/MP_0001830

文献

http://purl.org/net/cito/citesAsAuthority

• Yuhang. Zhang, et.al., Conditional Fas-associated death domain protein (FADD): GFP knockout mice reveal FADD is dispensable in thymic development but essential in peripheral T cell homeostasis., Journal of immunology (Baltimore, Md. : 1950), 2005, 175
  http://rdf.ncbi.nlm.nih.gov/pubmed/16116191