increased inflammatory response_Pdcd1<tm1Hon>/Pdcd1<tm1Hon>,Vsir<tm1Lex>/Vsir<tm1Lex>

http://metadb.riken.jp/0001846I129S2SvPas129S5SvEvBrdC57BL6Pdcd1tm1HonPdcd1tm1HonVsirtm1LexVsirtm1LexVsirtm1LexPdcd1tm1Hon

increased inflammatory response_Pdcd1<tm1Hon>/Pdcd1<tm1Hon>,Vsir<tm1Lex>/Vsir<tm1Lex>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• V-set immunoregulatory receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:1921298
• programmed cell death 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:104879

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pdcd1<tm1Hon>/Pdcd1<tm1Hon>,Vsir<tm1Lex>/Vsir<tm1Lex>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Vsir<tm1Lex>|Pdcd1<tm1Hon>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased inflammatory response
  http://purl.obolibrary.org/obo/MP_0001846

文献

http://purl.org/net/cito/citesAsAuthority

• Jun. Liu, et.al., Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses., Proceedings of the National Academy of Sciences of the United States of America, 2015, 112
  http://rdf.ncbi.nlm.nih.gov/pubmed/25964334