increased inflammatory response_Nlrp3<tm1Hhf>/Nlrp3<+>,Tg(Zp3-cre)3Mrt/?

http://metadb.riken.jp/0001846I129SvFVBNNlrp3tm1HhfNlrp3TgZp3cre3MrtNlrp3tm1HhfNlrp3TgZp3cre3Mrt

increased inflammatory response_Nlrp3<tm1Hhf>/Nlrp3<+>,Tg(Zp3-cre)3Mrt/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 3, Gail R Martin
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176051
• NLR family, pyrin domain containing 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2653833

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nlrp3<tm1Hhf>/Nlrp3<+>,Tg(Zp3-cre)3Mrt/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nlrp3<tm1Hhf>|Nlrp3<+>|Tg(Zp3-cre)3Mrt

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased inflammatory response
  http://purl.obolibrary.org/obo/MP_0001846

文献

http://purl.org/net/cito/citesAsAuthority

• Susannah D. Brydges, et.al., Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity., Immunity, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19501000