decreased inflammatory response_Alox5<tm1Fun>/Alox5<tm1Fun>

http://metadb.riken.jp/0001876I129S2SvPasC57BL6Alox5tm1FunAlox5tm1FunAlox5tm1Fun

decreased inflammatory response_Alox5<tm1Fun>/Alox5<tm1Fun>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• arachidonate 5-lipoxygenase
  http://metadb.riken.jp/db/mgi_rdf/MGI:87999

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Alox5<tm1Fun>/Alox5<tm1Fun>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Alox5<tm1Fun>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased inflammatory response
  http://purl.obolibrary.org/obo/MP_0001876

文献

http://purl.org/net/cito/citesAsAuthority

• Brahm H. Segal, et.al., Thioglycollate peritonitis in mice lacking C5, 5-lipoxygenase, or p47(phox): complement, leukotrienes, and reactive oxidants in acute inflammation., Journal of leukocyte biology, 2002, 71
  http://rdf.ncbi.nlm.nih.gov/pubmed/11867678
• X S. Chen, et.al., Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene., Nature, 1994, 372
  http://rdf.ncbi.nlm.nih.gov/pubmed/7969451