increased mammary adenocarcinoma incidence_Akt1<Gt1Pnt>/Akt1<Gt1Pnt>,Tg(MMTV-PyVT)634Mul/0

http://metadb.riken.jp/0001883I129C57BL6FVBNAkt1Gt1PntAkt1Gt1PntTgMMTVPyVT634Mul0TgMMTVPyVT634MulAkt1Gt1Pnt

increased mammary adenocarcinoma incidence_Akt1<Gt1Pnt>/Akt1<Gt1Pnt>,Tg(MMTV-PyVT)634Mul/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 634, William Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679594
• thymoma viral proto-oncogene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:87986

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Akt1<Gt1Pnt>/Akt1<Gt1Pnt>,Tg(MMTV-PyVT)634Mul/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(MMTV-PyVT)634Mul|Akt1<Gt1Pnt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0001883

文献

http://purl.org/net/cito/citesAsAuthority

• Ioanna G. Maroulakou, et.al., Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice., Cancer research, 2007, 67
  http://rdf.ncbi.nlm.nih.gov/pubmed/17210696