increased mammary adenocarcinoma incidence_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Tg(Wnt1)1Hev/0

http://metadb.riken.jp/0001883I129P2OlaHsdC57BL6SJLEsr1tm1KskEsr1tm1KskTgWnt11Hev0Esr1tm1KskTgWnt11Hev

increased mammary adenocarcinoma incidence_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Tg(Wnt1)1Hev/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Harold E Varmus
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890060
• estrogen receptor 1 (alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1352467

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Esr1<tm1Ksk>/Esr1<tm1Ksk>,Tg(Wnt1)1Hev/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Esr1<tm1Ksk>|Tg(Wnt1)1Hev

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0001883

文献

http://purl.org/net/cito/citesAsAuthority

• W P. Bocchinfuso, et.al., A mouse mammary tumor virus-Wnt-1 transgene induces mammary gland hyperplasia and tumorigenesis in mice lacking estrogen receptor-alpha., Cancer research, 1999, 59
  http://rdf.ncbi.nlm.nih.gov/pubmed/10213494