increased mammary adenocarcinoma incidence_Brca1<tm1Thl>/Brca1<tm1Thl>,Wap<tm1(cre)Arge>/0

http://metadb.riken.jp/0001883I129S1SvC57BL6JBrca1tm1ThlBrca1tm1ThlWaptm1creArge0Brca1tm1ThlWaptm1creArge

increased mammary adenocarcinoma incidence_Brca1<tm1Thl>/Brca1<tm1Thl>,Wap<tm1(cre)Arge>/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• breast cancer 1, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:104537
• whey acidic protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:98943

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca1<tm1Thl>/Brca1<tm1Thl>,Wap<tm1(cre)Arge>/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Brca1<tm1Thl>|Wap<tm1(cre)Arge>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0001883

文献

http://purl.org/net/cito/citesAsAuthority

• Reena. Shakya, et.al., The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/18443292