increased mammary adenocarcinoma incidence_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Tg(MMTV-vHaras)SH1Led/0

http://metadb.riken.jp/0001883I129S2SvPasC57BL6JCD1FVBNCdkn1atm1TyjCdkn1atm1TyjTgMMTVvHarasSH1Led0Cdkn1atm1TyjTgMMTVvHarasSH1Led

increased mammary adenocarcinoma incidence_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Tg(MMTV-vHaras)SH1Led/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion SH1, Philip Leder
  http://metadb.riken.jp/db/mgi_rdf/MGI:2653621
• cyclin-dependent kinase inhibitor 1A (P21)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104556

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Tg(MMTV-vHaras)SH1Led/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn1a<tm1Tyj>|Tg(MMTV-vHaras)SH1Led

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6J * CD-1 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0001883

文献

http://purl.org/net/cito/citesAsAuthority

• J. Adnane, et.al., Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model., Oncogene, 2000, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/11103935