increased mammary adenocarcinoma incidence_Trp53<tm3Tyj>/Trp53<+>,Tg(Wap-cre)11738Mam/0

http://metadb.riken.jp/0001883I129S4SvJaeC57BL6SJLTrp53tm3TyjTrp53TgWapcre11738Mam0Trp53TgWapcre11738MamTrp53tm3Tyj

increased mammary adenocarcinoma incidence_Trp53<tm3Tyj>/Trp53<+>,Tg(Wap-cre)11738Mam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 11738, Lothar Hennighausen
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176164

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm3Tyj>/Trp53<+>,Tg(Wap-cre)11738Mam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<+>|Tg(Wap-cre)11738Mam|Trp53<tm3Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0001883

文献

http://purl.org/net/cito/citesAsAuthority

• Susan W P. Wijnhoven, et.al., Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development., Cancer research, 2005, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/16166291