increased mammary adenocarcinoma incidence_Trp53<tm1Elee>/Trp53<tm1Elee>,Tg(Wap-rtTA-cre)10Whl/0

http://metadb.riken.jp/0001883I129S4SvJaeC57BL6Trp53tm1EleeTrp53tm1EleeTgWaprtTAcre10Whl0TgWaprtTAcre10WhlTrp53tm1Elee

increased mammary adenocarcinoma incidence_Trp53<tm1Elee>/Trp53<tm1Elee>,Tg(Wap-rtTA-cre)10Whl/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 10, Wen-Hwa Lee
  http://metadb.riken.jp/db/mgi_rdf/MGI:2673264

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Elee>/Trp53<tm1Elee>,Tg(Wap-rtTA-cre)10Whl/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Wap-rtTA-cre)10Whl|Trp53<tm1Elee>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0001883

文献

http://purl.org/net/cito/citesAsAuthority

• Suh-Chin J. Lin, et.al., Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis., Cancer research, 2004, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/15150107