mammary gland alveolar hyperplasia_Brca1<tm2Cxd>/Brca1<tm2Cxd>,Tg(MMTV-cre)4Mam/0

http://metadb.riken.jp/0001884I129S6SvEvTacC57BL6FVBBrca1tm2CxdBrca1tm2CxdTgMMTVcre4Mam0TgMMTVcre4MamBrca1tm2Cxd

mammary gland alveolar hyperplasia_Brca1<tm2Cxd>/Brca1<tm2Cxd>,Tg(MMTV-cre)4Mam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 4, Lothar Hennighausen
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176163
• breast cancer 1, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:104537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca1<tm2Cxd>/Brca1<tm2Cxd>,Tg(MMTV-cre)4Mam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(MMTV-cre)4Mam|Brca1<tm2Cxd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• mammary gland alveolar hyperplasia
  http://purl.obolibrary.org/obo/MP_0001884

文献

http://purl.org/net/cito/citesAsAuthority

• L P. Jones, et.al., Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer., Oncogene, 2008, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17653086