absence of NMDA-mediated synaptic currents_Grin1<tm1Rsp>/Grin1<tm1Rsp>,Tg(Gnrh1-cre)1Rsp/0

http://metadb.riken.jp/0001901IC57BL6Grin1tm1RspGrin1tm1RspTgGnrh1cre1Rsp0TgGnrh1cre1RspGrin1tm1Rsp

absence of NMDA-mediated synaptic currents_Grin1<tm1Rsp>/Grin1<tm1Rsp>,Tg(Gnrh1-cre)1Rsp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glutamate receptor, ionotropic, NMDA1 (zeta 1)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95819
• transgene insertion 1, Rolf Sprengel
  http://metadb.riken.jp/db/mgi_rdf/MGI:3612428

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grin1<tm1Rsp>/Grin1<tm1Rsp>,Tg(Gnrh1-cre)1Rsp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Gnrh1-cre)1Rsp|Grin1<tm1Rsp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• absence of NMDA-mediated synaptic currents
  http://purl.obolibrary.org/obo/MP_0001901

文献

http://purl.org/net/cito/citesAsAuthority

• Derya R. Shimshek, et.al., Impaired reproductive behavior by lack of GluR-B containing AMPA receptors but not of NMDA receptors in hypothalamic and septal neurons., Molecular endocrinology (Baltimore, Md.), 2006, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/16099814