increased dopamine level_Park2<tm1Ykt>/Park2<tm1Ykt>

http://metadb.riken.jp/0001906I129P2OlaHsdC57BL6Park2tm1YktPark2tm1YktPark2tm1Ykt

increased dopamine level_Park2<tm1Ykt>/Park2<tm1Ykt>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Parkinson disease (autosomal recessive, juvenile) 2, parkin
  http://metadb.riken.jp/db/mgi_rdf/MGI:1355296

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Park2<tm1Ykt>/Park2<tm1Ykt>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Park2<tm1Ykt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased dopamine level
  http://purl.obolibrary.org/obo/MP_0001906

文献

http://purl.org/net/cito/citesAsAuthority

• Yasuko. Kitao, et.al., Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation., Human molecular genetics, 2007, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/17116640