reduced fertility_Smn1<tm1Msd>/Smn1<tm1Msd>,Tg(SMN1*A2G)2023Ahmb/0,Grm7<Tg(SMN2)89Ahmb>/0

http://metadb.riken.jp/0001921I129P2OlaHsdFVBNSmn1tm1MsdSmn1tm1MsdTgSMN1A2G2023Ahmb0Grm7TgSMN289Ahmb0Smn1tm1MsdGrm7TgSMN289AhmbTgSMN1A2G2023Ahmb

reduced fertility_Smn1<tm1Msd>/Smn1<tm1Msd>,Tg(SMN1*A2G)2023Ahmb/0,Grm7<Tg(SMN2)89Ahmb>/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2023, Arthur H M Burghes
  http://metadb.riken.jp/db/mgi_rdf/MGI:3033247
• glutamate receptor, metabotropic 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1351344
• survival motor neuron 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109257

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Smn1<tm1Msd>/Smn1<tm1Msd>,Tg(SMN1*A2G)2023Ahmb/0,Grm7<Tg(SMN2)89Ahmb>/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smn1<tm1Msd>|Grm7<Tg(SMN2)89Ahmb>|Tg(SMN1*A2G)2023Ahmb

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• reduced fertility
  http://purl.obolibrary.org/obo/MP_0001921

文献

http://purl.org/net/cito/citesAsAuthority

• Umrao R. Monani, et.al., A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy., The Journal of cell biology, 2003, 160
  http://rdf.ncbi.nlm.nih.gov/pubmed/12515823