decreased litter size_Ghr<tm1Jjk>/Ghr<tm1Jjk>

http://metadb.riken.jp/0001935I129P2OlaHsdBALBcGhrtm1JjkGhrtm1JjkGhrtm1Jjk

decreased litter size_Ghr<tm1Jjk>/Ghr<tm1Jjk>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• growth hormone receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:95708

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ghr<tm1Jjk>/Ghr<tm1Jjk>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ghr<tm1Jjk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * BALB/c

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased litter size
  http://purl.obolibrary.org/obo/MP_0001935

文献

http://purl.org/net/cito/citesAsAuthority

• Denise. Zaczek, et.al., Impact of growth hormone resistance on female reproductive function: new insights from growth hormone receptor knockout mice., Biology of reproduction, 2002, 67
  http://rdf.ncbi.nlm.nih.gov/pubmed/12297526
• N. Danilovich, et.al., Deficits in female reproductive function in GH-R-KO mice; role of IGF-I., Endocrinology, 1999, 140
  http://rdf.ncbi.nlm.nih.gov/pubmed/10342852
• Y. Zhou, et.al., A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9371826