delayed sexual maturation_Kiss1r<tm1.1Hjn>/Kiss1r<tm1.1Hjn>,Tg(Gnrh1-cre)35Awo/0

http://metadb.riken.jp/0001938I129C57BL6CD1Kiss1rtm11HjnKiss1rtm11HjnTgGnrh1cre35Awo0Kiss1rtm11HjnTgGnrh1cre35Awo

delayed sexual maturation_Kiss1r<tm1.1Hjn>/Kiss1r<tm1.1Hjn>,Tg(Gnrh1-cre)35Awo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 35, Andrew Wolfe
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437079
• KISS1 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:2148793

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kiss1r<tm1.1Hjn>/Kiss1r<tm1.1Hjn>,Tg(Gnrh1-cre)35Awo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kiss1r<tm1.1Hjn>|Tg(Gnrh1-cre)35Awo

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• delayed sexual maturation
  http://purl.obolibrary.org/obo/MP_0001938

文献

http://purl.org/net/cito/citesAsAuthority

• Horacio J. Novaira, et.al., Disrupted kisspeptin signaling in GnRH neurons leads to hypogonadotrophic hypogonadism., Molecular endocrinology (Baltimore, Md.), 2014, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/24422632