increased chemically-elicited antinociception_Cnr1<tm1.1Kpm>/Cnr1<tm1.1Kpm>

http://metadb.riken.jp/0001981I129S1Sv129X1SvJC57BL6JCnr1tm11KpmCnr1tm11KpmCnr1tm11Kpm

increased chemically-elicited antinociception_Cnr1<tm1.1Kpm>/Cnr1<tm1.1Kpm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cannabinoid receptor 1 (brain)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104615

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cnr1<tm1.1Kpm>/Cnr1<tm1.1Kpm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cnr1<tm1.1Kpm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased chemically-elicited antinociception
  http://purl.obolibrary.org/obo/MP_0001981

文献

http://purl.org/net/cito/citesAsAuthority

• Daniel J. Morgan, et.al., Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, 34
  http://rdf.ncbi.nlm.nih.gov/pubmed/24719095