increased cellular sensitivity to gamma-irradiation_Mcm8<tm1.1Geno>/Mcm8<tm1.1Geno>

http://metadb.riken.jp/0002007I129S2SvPasC57BL6JMcm8tm11GenoMcm8tm11GenoMcm8tm11Geno

increased cellular sensitivity to gamma-irradiation_Mcm8<tm1.1Geno>/Mcm8<tm1.1Geno>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• minichromosome maintenance 8 homologous recombination repair factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913884

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mcm8<tm1.1Geno>/Mcm8<tm1.1Geno>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mcm8<tm1.1Geno>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cellular sensitivity to gamma-irradiation
  http://purl.obolibrary.org/obo/MP_0002007

文献

http://purl.org/net/cito/citesAsAuthority

• Malik. Lutzmann, et.al., MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination., Molecular cell, 2012, 47
  http://rdf.ncbi.nlm.nih.gov/pubmed/22771120