increased cellular sensitivity to gamma-irradiation_Ddx5<tm1.1Arte>/Ddx5<tm1.1Arte>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0002007IC57BL6NC57BL6NTacDdx5tm11ArteDdx5tm11ArteGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorDdx5tm11Arte

increased cellular sensitivity to gamma-irradiation_Ddx5<tm1.1Arte>/Ddx5<tm1.1Arte>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:105037

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ddx5<tm1.1Arte>/Ddx5<tm1.1Arte>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>|Gt(ROSA)26Sor<+>|Ddx5<tm1.1Arte>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6N * C57BL/6NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cellular sensitivity to gamma-irradiation
  http://purl.obolibrary.org/obo/MP_0002007

文献

http://purl.org/net/cito/citesAsAuthority

• S M. Nicol, et.al., The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage., Oncogene, 2013, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/22986526