increased malignant tumor incidence_Fen1<tm1Rak>/Fen1<+>,Apc<tm1Rak>/Apc<+>

http://metadb.riken.jp/0002018I129Sv129P2OlaHsdC57BL6SJLJFen1tm1RakFen1Apctm1RakApcFen1Apctm1RakFen1tm1RakApc

increased malignant tumor incidence_Fen1<tm1Rak>/Fen1<+>,Apc<tm1Rak>/Apc<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• flap structure specific endonuclease 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:102779
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fen1<tm1Rak>/Fen1<+>,Apc<tm1Rak>/Apc<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fen1<+>|Apc<tm1Rak>|Fen1<tm1Rak>|Apc<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * SJL/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased malignant tumor incidence
  http://purl.obolibrary.org/obo/MP_0002018

文献

http://purl.org/net/cito/citesAsAuthority

• Melanie. Kucherlapati, et.al., Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99
  http://rdf.ncbi.nlm.nih.gov/pubmed/12119409