increased tumor incidence_Cdkn1a<tm1Led>/Cdkn1a<tm1Led>,Wrn<tm1Led>/Wrn<tm1Led>

http://metadb.riken.jp/0002020EI129S6SvEvTacorI129S6SvEvTacNIHBlackSwissCdkn1atm1LedCdkn1atm1LedWrntm1LedWrntm1LedWrntm1LedCdkn1atm1Led

increased tumor incidence_Cdkn1a<tm1Led>/Cdkn1a<tm1Led>,Wrn<tm1Led>/Wrn<tm1Led>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 1A (P21)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104556
• Werner syndrome RecQ like helicase
  http://metadb.riken.jp/db/mgi_rdf/MGI:109635

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1a<tm1Led>/Cdkn1a<tm1Led>,Wrn<tm1Led>/Wrn<tm1Led>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Wrn<tm1Led>|Cdkn1a<tm1Led>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002020

文献

http://purl.org/net/cito/citesAsAuthority

• M. Lebel, et.al., Tumorigenic effect of nonfunctional p53 or p21 in mice mutant in the Werner syndrome helicase., Cancer research, 2001, 61
  http://rdf.ncbi.nlm.nih.gov/pubmed/11280729