increased tumor incidence_Trp53<tm1Brd>/Trp53<tm1Brd>,Wrn<tm1Led>/Wrn<tm1Led>

http://metadb.riken.jp/0002020EI129SSvEvorI129SSvEvNIHBlackSwissTrp53tm1BrdTrp53tm1BrdWrntm1LedWrntm1LedWrntm1LedTrp53tm1Brd

increased tumor incidence_Trp53<tm1Brd>/Trp53<tm1Brd>,Wrn<tm1Led>/Wrn<tm1Led>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Werner syndrome RecQ like helicase
  http://metadb.riken.jp/db/mgi_rdf/MGI:109635
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Brd>/Trp53<tm1Brd>,Wrn<tm1Led>/Wrn<tm1Led>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Wrn<tm1Led>|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S/SvEv) or (involves: 129S/SvEv * NIH Black Swiss)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002020

文献

http://purl.org/net/cito/citesAsAuthority

• M. Lebel, et.al., Tumorigenic effect of nonfunctional p53 or p21 in mice mutant in the Werner syndrome helicase., Cancer research, 2001, 61
  http://rdf.ncbi.nlm.nih.gov/pubmed/11280729