increased tumor incidence_Ppm1d<tm1Lad>/Ppm1d<tm1Lad>,Tg(IghMyc)22Bri/0,Trp53<tm1Brd>/Trp53<+>

http://metadb.riken.jp/0002020I129C57BLFVBNSJLPpm1dtm1LadPpm1dtm1LadTgIghMyc22Bri0Trp53tm1BrdTrp53Trp53Trp53tm1BrdTgIghMyc22BriPpm1dtm1Lad

increased tumor incidence_Ppm1d<tm1Lad>/Ppm1d<tm1Lad>,Tg(IghMyc)22Bri/0,Trp53<tm1Brd>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 22, Ralph L Brinster
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448238
• protein phosphatase 1D magnesium-dependent, delta isoform
  http://metadb.riken.jp/db/mgi_rdf/MGI:1858214

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ppm1d<tm1Lad>/Ppm1d<tm1Lad>,Tg(IghMyc)22Bri/0,Trp53<tm1Brd>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<+>|Trp53<tm1Brd>|Tg(IghMyc)22Bri|Ppm1d<tm1Lad>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002020

文献

http://purl.org/net/cito/citesAsAuthority

• Sathyavageeswaran. Shreeram, et.al., Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase., The Journal of experimental medicine, 2006, 203
  http://rdf.ncbi.nlm.nih.gov/pubmed/17158963