increased tumor incidence_Trp53<tm1Brd>/Trp53<+>,Trp53bp2<tm1Cdlo>/Trp53bp2<+>

http://metadb.riken.jp/0002020I129S1Sv129S7SvEvBrd129X1SvJC57BL6Trp53tm1BrdTrp53Trp53bp2tm1CdloTrp53bp2Trp53bp2Trp53Trp53bp2tm1CdloTrp53tm1Brd

increased tumor incidence_Trp53<tm1Brd>/Trp53<+>,Trp53bp2<tm1Cdlo>/Trp53bp2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transformation related protein 53 binding protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2138319

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Brd>/Trp53<+>,Trp53bp2<tm1Cdlo>/Trp53bp2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53bp2<+>|Trp53<+>|Trp53bp2<tm1Cdlo>|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002020

文献

http://purl.org/net/cito/citesAsAuthority

• Kerstin M. Kampa, et.al., Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19251665