increased tumor incidence_Pold1<tm1Bdp>/Pold1<tm1Bdp>

http://metadb.riken.jp/0002020I129S1Sv129X1SvJC57BL6Pold1tm1BdpPold1tm1BdpPold1tm1Bdp

increased tumor incidence_Pold1<tm1Bdp>/Pold1<tm1Bdp>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• polymerase (DNA directed), delta 1, catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:97741

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pold1<tm1Bdp>/Pold1<tm1Bdp>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pold1<tm1Bdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002020

文献

http://purl.org/net/cito/citesAsAuthority

• R E. Goldsby, et.al., Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice., Nature medicine, 2001, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/11385474
• Robert E. Goldsby, et.al., High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99
  http://rdf.ncbi.nlm.nih.gov/pubmed/12429860