increased tumor incidence_Pold1<tm2Loeb>/Pold1<+>

http://metadb.riken.jp/0002020I129S1Sv129X1SvJC57BL6Pold1tm2LoebPold1Pold1Pold1tm2Loeb

increased tumor incidence_Pold1<tm2Loeb>/Pold1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• polymerase (DNA directed), delta 1, catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:97741

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pold1<tm2Loeb>/Pold1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pold1<+>|Pold1<tm2Loeb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002020

文献

http://purl.org/net/cito/citesAsAuthority

• Ranga N. Venkatesan, et.al., Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis., Molecular and cellular biology, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17785453