increased tumor incidence_Tg(Nes-cre)1Kln/0,Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0002020I129S6SvEvTac129S7SvEvBrdC57BL6SJLTgNescre1Kln0Trp53tm1BrdTrp53tm1BrdTgNescre1KlnTrp53tm1Brd

increased tumor incidence_Tg(Nes-cre)1Kln/0,Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Nes-cre)1Kln/0,Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Kln|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002020

文献

http://purl.org/net/cito/citesAsAuthority

• Catherine T. Yan, et.al., XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/16670198