increased tumor incidence_Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0002020I129S7SvEvBrdC57BL6Trp53tm1BrdTrp53tm1BrdTrp53tm1Brd

increased tumor incidence_Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002020

文献

http://purl.org/net/cito/citesAsAuthority

• L A. Donehower, et.al., Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours., Nature, 1992, 356
  http://rdf.ncbi.nlm.nih.gov/pubmed/1552940
• Franck. Toledo, et.al., A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network., Cancer cell, 2006, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/16616333