increased tumor incidence_Dmtf1<tm1Cjs>/Dmtf1<+>

http://metadb.riken.jp/0002020I129SvC57BL6Dmtf1tm1CjsDmtf1Dmtf1tm1CjsDmtf1

increased tumor incidence_Dmtf1<tm1Cjs>/Dmtf1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin D binding myb-like transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1344415

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dmtf1<tm1Cjs>/Dmtf1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dmtf1<tm1Cjs>|Dmtf1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002020

文献

http://purl.org/net/cito/citesAsAuthority

• K. Inoue, et.al., Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas., Genes & development, 2001, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/11711428
• K. Inoue, et.al., Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis., Genes & development, 2000, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/10898794