increased tumor incidence_Cdkn2a<tm1Rdp>/Cdkn2a<+>,Terc<tm1Rdp>/Terc<tm1Rdp>

http://metadb.riken.jp/0002020I129SvC57BL6JSJLCdkn2atm1RdpCdkn2aTerctm1RdpTerctm1RdpCdkn2atm1RdpCdkn2aTerctm1Rdp

increased tumor incidence_Cdkn2a<tm1Rdp>/Cdkn2a<+>,Terc<tm1Rdp>/Terc<tm1Rdp>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• telomerase RNA component
  http://metadb.riken.jp/db/mgi_rdf/MGI:109558
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<+>,Terc<tm1Rdp>/Terc<tm1Rdp>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2a<tm1Rdp>|Cdkn2a<+>|Terc<tm1Rdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002020

文献

http://purl.org/net/cito/citesAsAuthority

• Christine M. Khoo, et.al., Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/17360455