increased tumor incidence_Ryr2<tm1Nobs>/Ryr2<tm1Nobs>,Trp53<tm1Sia>/Trp53<tm1Sia>

http://metadb.riken.jp/0002020I129X1SvJC57BL6CBARyr2tm1NobsRyr2tm1NobsTrp53tm1SiaTrp53tm1SiaRyr2tm1NobsTrp53tm1Sia

increased tumor incidence_Ryr2<tm1Nobs>/Ryr2<tm1Nobs>,Trp53<tm1Sia>/Trp53<tm1Sia>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ryanodine receptor 2, cardiac
  http://metadb.riken.jp/db/mgi_rdf/MGI:99685
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ryr2<tm1Nobs>/Ryr2<tm1Nobs>,Trp53<tm1Sia>/Trp53<tm1Sia>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ryr2<tm1Nobs>|Trp53<tm1Sia>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002020

文献

http://purl.org/net/cito/citesAsAuthority

• H. Tsumura, et.al., Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice., Oncogene, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16785989