increased incidence of induced tumors_H2afx<tm1Nus>/H2afx<+>,Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0002021I129S7SvEvBrdC57BL6JH2afxtm1NusH2afxTrp53tm1BrdTrp53tm1BrdH2afxH2afxtm1NusTrp53tm1Brd

increased incidence of induced tumors_H2afx<tm1Nus>/H2afx<+>,Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• H2A histone family, member X
  http://metadb.riken.jp/db/mgi_rdf/MGI:102688
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• H2afx<tm1Nus>/H2afx<+>,Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• H2afx<+>|H2afx<tm1Nus>|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased incidence of induced tumors
  http://purl.obolibrary.org/obo/MP_0002021

文献

http://purl.org/net/cito/citesAsAuthority

• Arkady. Celeste, et.al., H2AX haploinsufficiency modifies genomic stability and tumor susceptibility., Cell, 2003, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/12914701