increased B cell derived lymphoma incidence_Kat5<tm1Jwl>/Kat5<+>,Tg(IghMyc)22Bri/0,Trp53<tm1Tyj>/Trp53<+>

http://metadb.riken.jp/0002023I129C57BLC57BL6SJLKat5tm1JwlKat5TgIghMyc22Bri0Trp53tm1TyjTrp53Kat5TgIghMyc22BriTrp53tm1TyjKat5tm1JwlTrp53

increased B cell derived lymphoma incidence_Kat5<tm1Jwl>/Kat5<+>,Tg(IghMyc)22Bri/0,Trp53<tm1Tyj>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• K(lysine) acetyltransferase 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1932051
• transgene insertion 22, Ralph L Brinster
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448238
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kat5<tm1Jwl>/Kat5<+>,Tg(IghMyc)22Bri/0,Trp53<tm1Tyj>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kat5<+>|Tg(IghMyc)22Bri|Trp53<tm1Tyj>|Kat5<tm1Jwl>|Trp53<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased B cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002023

文献

http://purl.org/net/cito/citesAsAuthority

• Chiara. Gorrini, et.al., Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response., Nature, 2007, 448
  http://rdf.ncbi.nlm.nih.gov/pubmed/17728759