increased B cell derived lymphoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Ly6e-MALT1)#Isg/0

http://metadb.riken.jp/0002023I129S2SvPasC57BL6CBATrp53tm1TyjTrp53tm1TyjTgLy6eMALT1Isg0Trp53tm1TyjTgLy6eMALT1Isg

increased B cell derived lymphoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Ly6e-MALT1)#Isg/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Isidro Sanchez-Garcia
  http://metadb.riken.jp/db/mgi_rdf/MGI:5432015
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Ly6e-MALT1)#Isg/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>|Tg(Ly6e-MALT1)#Isg

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased B cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002023

文献

http://purl.org/net/cito/citesAsAuthority

• Carolina. Vicente-Dueñas, et.al., Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/22689981