increased B cell derived lymphoma incidence_Dnmt1<tm1(tetO-BCL2)Sjk>/Dnmt1<+>,Tg(IghMyc)22Bri/0,Tg(MMTVtTA)1Mam/0

http://metadb.riken.jp/0002023I129S4SvJaeC57BL6Dnmt1tm1tetOBCL2SjkDnmt1TgIghMyc22Bri0TgMMTVtTA1Mam0Dnmt1Dnmt1tm1tetOBCL2SjkTgMMTVtTA1MamTgIghMyc22Bri

increased B cell derived lymphoma incidence_Dnmt1<tm1(tetO-BCL2)Sjk>/Dnmt1<+>,Tg(IghMyc)22Bri/0,Tg(MMTVtTA)1Mam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 22, Ralph L Brinster
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448238
• transgene insertion 1, Lothar Hennighausen
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053971
• DNA methyltransferase (cytosine-5) 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:94912

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dnmt1<tm1(tetO-BCL2)Sjk>/Dnmt1<+>,Tg(IghMyc)22Bri/0,Tg(MMTVtTA)1Mam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dnmt1<+>|Dnmt1<tm1(tetO-BCL2)Sjk>|Tg(MMTVtTA)1Mam|Tg(IghMyc)22Bri

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased B cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002023

文献

http://purl.org/net/cito/citesAsAuthority

• Anthony. Letai, et.al., Antiapoptotic BCL-2 is required for maintenance of a model leukemia., Cancer cell, 2004, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/15380515