increased B cell derived lymphoma incidence_Igh<tm1(Myc)Janz>/Igh<+>

http://metadb.riken.jp/0002023I129X1SvJC57BL6Ightm1MycJanzIghIghtm1MycJanzIgh

increased B cell derived lymphoma incidence_Igh<tm1(Myc)Janz>/Igh<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh<tm1(Myc)Janz>/Igh<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igh<tm1(Myc)Janz>|Igh<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased B cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002023

文献

http://purl.org/net/cito/citesAsAuthority

• Sung Sup. Park, et.al., Insertion of c-Myc into Igh induces B-cell and plasma-cell neoplasms in mice., Cancer research, 2005, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/15735016
• A. Zingone, et.al., Ectopic expression of wild-type FGFR3 cooperates with MYC to accelerate development of B-cell lineage neoplasms., Leukemia, 2010, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/20393505