increased B cell derived lymphoma incidence_Ube2o<tm1.1(KOMP)Mbp>/Ube2o<tm1.1(KOMP)Mbp>,Tg(IghMyc)22Bri/0

http://metadb.riken.jp/0002023IC57BLC57BL6NFVBNSJLUbe2otm11KOMPMbpUbe2otm11KOMPMbpTgIghMyc22Bri0TgIghMyc22BriUbe2otm11KOMPMbp

increased B cell derived lymphoma incidence_Ube2o<tm1.1(KOMP)Mbp>/Ube2o<tm1.1(KOMP)Mbp>,Tg(IghMyc)22Bri/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 22, Ralph L Brinster
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448238
• ubiquitin-conjugating enzyme E2O
  http://metadb.riken.jp/db/mgi_rdf/MGI:2444266

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ube2o<tm1.1(KOMP)Mbp>/Ube2o<tm1.1(KOMP)Mbp>,Tg(IghMyc)22Bri/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(IghMyc)22Bri|Ube2o<tm1.1(KOMP)Mbp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL * C57BL/6N * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased B cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002023

文献

http://purl.org/net/cito/citesAsAuthority

• Isabelle K. Vila, et.al., A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy., Cancer cell, 2017, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/28162974