increased T cell derived lymphoma incidence_Cdkn1b<tm1Mlf>/Cdkn1b<+>,Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(MMTV-cre)4Mam/0

http://metadb.riken.jp/0002024I129C57BL6CBAFVBCdkn1btm1MlfCdkn1bCrebbptm1JvdCrebbptm1JvdTgMMTVcre4Mam0Crebbptm1JvdCdkn1btm1MlfCdkn1bTgMMTVcre4Mam

increased T cell derived lymphoma incidence_Cdkn1b<tm1Mlf>/Cdkn1b<+>,Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(MMTV-cre)4Mam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 1B
  http://metadb.riken.jp/db/mgi_rdf/MGI:104565
• transgene insertion 4, Lothar Hennighausen
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176163
• CREB binding protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:1098280

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1b<tm1Mlf>/Cdkn1b<+>,Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(MMTV-cre)4Mam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Crebbp<tm1Jvd>|Cdkn1b<tm1Mlf>|Cdkn1b<+>|Tg(MMTV-cre)4Mam

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002024

文献

http://purl.org/net/cito/citesAsAuthority

• Ningling. Kang-Decker, et.al., Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency., Cancer cell, 2004, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/14998493