increased T cell derived lymphoma incidence_Tcrbe<tm1Che>/Tcrbe<tm1Che>,Tcrd<tm1Mom>/Tcrd<tm1Mom>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

http://metadb.riken.jp/0002024I129P2OlaHsd129S2SvPas129S4SvJaeC57BL6Tcrbetm1CheTcrbetm1CheTcrdtm1MomTcrdtm1MomTrp53tm1TyjTrp53tm1TyjTcrdtm1MomTrp53tm1TyjTcrbetm1Che

increased T cell derived lymphoma incidence_Tcrbe<tm1Che>/Tcrbe<tm1Che>,Tcrd<tm1Mom>/Tcrd<tm1Mom>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• T cell receptor delta chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:98611
• T cell receptor beta chain enhancer
  http://metadb.riken.jp/db/mgi_rdf/MGI:892967
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tcrbe<tm1Che>/Tcrbe<tm1Che>,Tcrd<tm1Mom>/Tcrd<tm1Mom>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tcrd<tm1Mom>|Trp53<tm1Tyj>|Tcrbe<tm1Che>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002024

文献

http://purl.org/net/cito/citesAsAuthority

• Brian B. Haines, et.al., Block of T cell development in P53-deficient mice accelerates development of lymphomas with characteristic RAG-dependent cytogenetic alterations., Cancer cell, 2006, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/16473278