increased T cell derived lymphoma incidence_Rev3l<tm1Rwd>/Rev3l<tm2.1Rwd>,Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(MMTV-cre)1Mam/0

http://metadb.riken.jp/0002024I129P2OlaHsd129S7SvEvBrdC57BL6FVBNRev3ltm1RwdRev3ltm21RwdTrp53tm1BrdTrp53tm1BrdTgMMTVcre1Mam0Rev3ltm1RwdRev3ltm21RwdTgMMTVcre1MamTrp53tm1Brd

increased T cell derived lymphoma incidence_Rev3l<tm1Rwd>/Rev3l<tm2.1Rwd>,Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(MMTV-cre)1Mam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Lothar Hennighausen
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176162
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• REV3 like, DNA directed polymerase zeta catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:1337131

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rev3l<tm1Rwd>/Rev3l<tm2.1Rwd>,Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(MMTV-cre)1Mam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rev3l<tm1Rwd>|Rev3l<tm2.1Rwd>|Tg(MMTV-cre)1Mam|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002024

文献

http://purl.org/net/cito/citesAsAuthority

• John P. Wittschieben, et.al., Loss of DNA polymerase zeta enhances spontaneous tumorigenesis., Cancer research, 2010, 70
  http://rdf.ncbi.nlm.nih.gov/pubmed/20215524