increased T cell derived lymphoma incidence_Trp53bp2<tm1Cdlo>/Trp53bp2<+>,Tg(EmuSR-tTa)83Bop/0,Tg(tetO-MYC)36aBop/0

http://metadb.riken.jp/0002024I129S1Sv129X1SvJC57BL6FVBNTrp53bp2tm1CdloTrp53bp2TgEmuSRtTa83Bop0TgtetOMYC36aBop0Trp53bp2TgtetOMYC36aBopTgEmuSRtTa83BopTrp53bp2tm1Cdlo

increased T cell derived lymphoma incidence_Trp53bp2<tm1Cdlo>/Trp53bp2<+>,Tg(EmuSR-tTa)83Bop/0,Tg(tetO-MYC)36aBop/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53 binding protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2138319
• transgene insertion 36a, J Michael Bishop
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459071
• transgene insertion 83, J Michael Bishop
  http://metadb.riken.jp/db/mgi_rdf/MGI:3040387

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53bp2<tm1Cdlo>/Trp53bp2<+>,Tg(EmuSR-tTa)83Bop/0,Tg(tetO-MYC)36aBop/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53bp2<+>|Tg(tetO-MYC)36aBop|Tg(EmuSR-tTa)83Bop|Trp53bp2<tm1Cdlo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002024

文献

http://purl.org/net/cito/citesAsAuthority

• Kerstin M. Kampa, et.al., Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19251665