increased T cell derived lymphoma incidence_Foxo1<tm1Rdp>/Foxo1<tm1Rdp>,Foxo3<tm1Rdp>/Foxo3<tm1Rdp>,Foxo4<tm1Rdp>/Foxo4<tm1Rdp>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0002024I129S6SvEvTacC57BL6CBAFVBNFoxo1tm1RdpFoxo1tm1RdpFoxo3tm1RdpFoxo3tm1RdpFoxo4tm1RdpFoxo4tm1RdpTgMx1cre1Cgn0TgMx1cre1CgnFoxo4tm1RdpFoxo3tm1RdpFoxo1tm1Rdp

increased T cell derived lymphoma incidence_Foxo1<tm1Rdp>/Foxo1<tm1Rdp>,Foxo3<tm1Rdp>/Foxo3<tm1Rdp>,Foxo4<tm1Rdp>/Foxo4<tm1Rdp>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• forkhead box O1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890077
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• forkhead box O3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890081
• forkhead box O4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891915

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxo1<tm1Rdp>/Foxo1<tm1Rdp>,Foxo3<tm1Rdp>/Foxo3<tm1Rdp>,Foxo4<tm1Rdp>/Foxo4<tm1Rdp>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Foxo4<tm1Rdp>|Foxo3<tm1Rdp>|Foxo1<tm1Rdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002024

文献

http://purl.org/net/cito/citesAsAuthority

• Ji-Hye. Paik, et.al., FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis., Cell, 2007, 128
  http://rdf.ncbi.nlm.nih.gov/pubmed/17254969