increased T cell derived lymphoma incidence_Rag1<tm1Mom>/Rag1<tm1Mom>,Trp53<tm1Brd>/Trp53<tm1Brd>,Xrcc5<tm1Dbr>/Xrcc5<tm1Dbr>

http://metadb.riken.jp/0002024I129S7SvEvBrdC57BLRag1tm1MomRag1tm1MomTrp53tm1BrdTrp53tm1BrdXrcc5tm1DbrXrcc5tm1DbrRag1tm1MomTrp53tm1BrdXrcc5tm1Dbr

increased T cell derived lymphoma incidence_Rag1<tm1Mom>/Rag1<tm1Mom>,Trp53<tm1Brd>/Trp53<tm1Brd>,Xrcc5<tm1Dbr>/Xrcc5<tm1Dbr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• recombination activating gene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97848
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• X-ray repair complementing defective repair in Chinese hamster cells 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:104517

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rag1<tm1Mom>/Rag1<tm1Mom>,Trp53<tm1Brd>/Trp53<tm1Brd>,Xrcc5<tm1Dbr>/Xrcc5<tm1Dbr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rag1<tm1Mom>|Trp53<tm1Brd>|Xrcc5<tm1Dbr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002024

文献

http://purl.org/net/cito/citesAsAuthority

• V B. Holcomb, et.al., Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs., Oncogene, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16751807