increased T cell derived lymphoma incidence_Ikzf1<tm3Kge>/Ikzf1<tm3Kge>,Tg(CD2-icre)4Kio/?

http://metadb.riken.jp/0002024IC57BL10CBACaIkzf1tm3KgeIkzf1tm3KgeTgCD2icre4KioTgCD2icre4KioIkzf1tm3Kge

increased T cell derived lymphoma incidence_Ikzf1<tm3Kge>/Ikzf1<tm3Kge>,Tg(CD2-icre)4Kio/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 4, Dimitris Kioussis
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449946
• IKAROS family zinc finger 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342540

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ikzf1<tm3Kge>/Ikzf1<tm3Kge>,Tg(CD2-icre)4Kio/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CD2-icre)4Kio|Ikzf1<tm3Kge>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/10 * CBA/Ca

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002024

文献

http://purl.org/net/cito/citesAsAuthority

• Ila. Joshi, et.al., Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia., Nature immunology, 2014, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/24509510