increased leukemia incidence_Kmt2a<tm1.1(Sh3gl1)Lcc>/Kmt2a<+>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0002026I129P2OlaHsd129SSvEvC57BL6Kmt2atm11Sh3gl1LccKmt2aLyz2tm1creIfoLyz2Lyz2Lyz2tm1creIfoKmt2aKmt2atm11Sh3gl1Lcc

increased leukemia incidence_Kmt2a<tm1.1(Sh3gl1)Lcc>/Kmt2a<+>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897
• lysine (K)-specific methyltransferase 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:96995

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kmt2a<tm1.1(Sh3gl1)Lcc>/Kmt2a<+>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyz2<+>|Lyz2<tm1(cre)Ifo>|Kmt2a<+>|Kmt2a<tm1.1(Sh3gl1)Lcc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased leukemia incidence
  http://purl.obolibrary.org/obo/MP_0002026

文献

http://purl.org/net/cito/citesAsAuthority

• Ray Kit. Ng, et.al., Epigenetic dysregulation of leukaemic HOX code in MLL-rearranged leukaemia mouse model., The Journal of pathology, 2014, 232
  http://rdf.ncbi.nlm.nih.gov/pubmed/24122813